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Spacer acquisition rates determine the immunological diversity of the type II CRISPR-Cas immune response.
CRISPR-Cas systems provide acquired immunity in prokaryotes. Upon infection, short sequences from the phage genome, known as spacers, are inserted between the CRISPR repeats. Spacers are transcribed into small RNA molecules that guide nucleases to their targets. The forces that shape the distributio...
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| Publicado no: | Cell Host Microbe |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6640137/ https://ncbi.nlm.nih.gov/pubmed/30709780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.12.016 |
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