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CRISPR-Cas systems optimize their immune response by specifying the site of spacer integration
CRISPR-Cas systems defend prokaryotes against viruses and plasmids. Short DNA segments of the invader, known as spacers, are stored in the CRISPR array as immunological memories. New spacers are added invariably to the 5′ end of the array, therefore the first spacer matches the latest foreign threat...
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Publicado no: | Mol Cell |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5096952/ https://ncbi.nlm.nih.gov/pubmed/27618488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.08.038 |
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