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Cas9 cleavage of viral genomes generates immunological memories during the type II CRISPR-Cas response.
Type II CRISPR-Cas systems defend prokaryotes from bacteriophage infection through the acquisition of short viral DNA sequences known as spacers, that are transcribed into short RNA guides to specify the targets of the Cas9 nuclease. To counter the potentially devastating propagation of escaper phag...
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| Publicado no: | Cell Host Microbe |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7558852/ https://ncbi.nlm.nih.gov/pubmed/31585845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.09.002 |
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