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Adapting to new threats: the generation of memory by CRISPR-Cas immune systems

Clustered, regularly interspaced, short palindromic repeats (CRISPR) loci and their associated genes (cas) confer bacteria and archaea with adaptive immunity against phages and other invading genetic elements. A fundamental requirement of any immune system is the ability to build a memory of past in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Heler, Robert, Marraffini, Luciano A., Bikard, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104294/
https://ncbi.nlm.nih.gov/pubmed/24806524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12640
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