The orphan nuclear receptor LRH-1/NR5a2 critically regulates T cell functions

LRH-1 (liver receptor homolog-1/NR5a2) is an orphan nuclear receptor, which regulates glucose and lipid metabolism, as well as intestinal inflammation via the transcriptional control of intestinal glucocorticoid synthesis. Predominantly expressed in epithelial cells, its expression and role in immun...

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Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Seitz, Carina, Huang, Juan, Geiselhöringer, Anna-Lena, Galbani-Bianchi, Pamela, Michalek, Svenja, Phan, Truong San, Reinhold, Cindy, Dietrich, Lea, Schmidt, Christian, Corazza, Nadia, Delgado, M. Eugenia, Schnalzger, Theresa, Schoonjans, Kristina, Brunner, Thomas
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636985/
https://ncbi.nlm.nih.gov/pubmed/31328159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav9732
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