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A role for orphan nuclear receptor liver receptor homolog-1 (LRH-1, NR5A2) in primordial follicle activation

Liver receptor homolog-1 (NR5A2) is expressed specifically in granulosa cells of developing ovarian follicles where it regulates the late stages of follicle development and ovulation. To establish its effects earlier in the trajectory of follicular development, NR5A2 was depleted from granulosa cell...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Meinsohn, Marie-Charlotte, Hughes, Camilla H. K., Estienne, Anthony, Saatcioglu, Hatice D., Pépin, David, Duggavathi, Raj, Murphy, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7807074/
https://ncbi.nlm.nih.gov/pubmed/33441767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80178-4
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