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A role for orphan nuclear receptor liver receptor homolog-1 (LRH-1, NR5A2) in primordial follicle activation

Liver receptor homolog-1 (NR5A2) is expressed specifically in granulosa cells of developing ovarian follicles where it regulates the late stages of follicle development and ovulation. To establish its effects earlier in the trajectory of follicular development, NR5A2 was depleted from granulosa cell...

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Publicado en:Sci Rep
Main Authors: Meinsohn, Marie-Charlotte, Hughes, Camilla H. K., Estienne, Anthony, Saatcioglu, Hatice D., Pépin, David, Duggavathi, Raj, Murphy, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7807074/
https://ncbi.nlm.nih.gov/pubmed/33441767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80178-4
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