The orphan nuclear receptor LRH-1/NR5a2 critically regulates T cell functions

LRH-1 (liver receptor homolog-1/NR5a2) is an orphan nuclear receptor, which regulates glucose and lipid metabolism, as well as intestinal inflammation via the transcriptional control of intestinal glucocorticoid synthesis. Predominantly expressed in epithelial cells, its expression and role in immun...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Seitz, Carina, Huang, Juan, Geiselhöringer, Anna-Lena, Galbani-Bianchi, Pamela, Michalek, Svenja, Phan, Truong San, Reinhold, Cindy, Dietrich, Lea, Schmidt, Christian, Corazza, Nadia, Delgado, M. Eugenia, Schnalzger, Theresa, Schoonjans, Kristina, Brunner, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636985/
https://ncbi.nlm.nih.gov/pubmed/31328159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav9732
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