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NR4A orphan nuclear receptor family members, NR4A2 and NR4A3, regulate neutrophil number and survival

The lifespan of neutrophils is plastic and highly responsive to factors that regulate cellular survival. Defects in neutrophil number and survival are common to both hematologic disorders and chronic inflammatory diseases. At sites of inflammation, neutrophils respond to multiple signals that activa...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Prince, Lynne R., Prosseda, Svenja D., Higgins, Kathryn, Carlring, Jennifer, Prestwich, Elizabeth C., Ogryzko, Nikolay V., Rahman, Atiqur, Basran, Alexander, Falciani, Francesco, Taylor, Philip, Renshaw, Stephen A., Whyte, Moira K. B., Sabroe, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570679/
https://ncbi.nlm.nih.gov/pubmed/28637666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-03-770164
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