Increased Lysosomal Exocytosis Induced by Lysosomal Ca(2+) Channel Agonists Protects Human Dopaminergic Neurons from α-Synuclein Toxicity

The accumulation of misfolded proteins is a common pathological feature of many neurodegenerative disorders, including synucleinopathies such as Parkinson's disease (PD), which is characterized by the presence of α-synuclein (α-syn)-containing Lewy bodies. However, although recent studies have...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Tsunemi, Taiji, Perez-Rosello, Tamara, Ishiguro, Yuta, Yoroisaka, Asako, Jeon, Sohee, Hamada, Kana, Rammonhan, Malini, Wong, Yvette C., Xie, Zhong, Akamatsu, Wado, Mazzulli, Joseph R., Surmeier, D. James, Hattori, Nobutaka, Krainc, Dimitri
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2019
Onderwerpen:
Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636071/
https://ncbi.nlm.nih.gov/pubmed/31097622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3085-18.2019
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items