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Parkin Modulates Endosomal Organization and Function of the Endo-Lysosomal Pathway
Mutations in PARK2 (parkin), which encodes Parkin protein, an E3 ubiquitin ligase, are associated with autosomal recessive early-onset Parkinson's disease (PD). While several studies implicated Parkin in the regulation of mitophagy and proteasomal degradation, the precise mechanism leading to n...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6705497/ https://ncbi.nlm.nih.gov/pubmed/26911690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2569-15.2016 |
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