Astrocytes Protect Human Dopaminergic Neurons from α-Synuclein Accumulation and Propagation

The pathologic hallmark of Parkinson's disease is the accumulation of α-synuclein-containing Lewy bodies/neurites almost exclusively in neurons, and rarely in glial cells. However, emerging evidence suggests that glia such as astrocytes play an important role in the development of α-synuclein p...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Tsunemi, Taiji, Ishiguro, Yuta, Yoroisaka, Asako, Valdez, Clarissa, Miyamoto, Kengo, Ishikawa, Keiichi, Saiki, Shinji, Akamatsu, Wado, Hattori, Nobutaka, Krainc, Dimitri
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2020
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643299/
https://ncbi.nlm.nih.gov/pubmed/33046546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0954-20.2020
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