Establishment of an in vitro model for analyzing mitochondrial ultrastructure in PRKN-mutated patient iPSC-derived dopaminergic neurons

Mitochondrial structural changes are associated with the regulation of mitochondrial function, apoptosis, and neurodegenerative diseases. PRKN is known to be involved with various mechanisms of mitochondrial quality control including mitochondrial structural changes. Parkinson’s disease (PD) with PR...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Yokota, Mutsumi, Kakuta, Soichiro, Shiga, Takahiro, Ishikawa, Kei-ichi, Okano, Hideyuki, Hattori, Nobutaka, Akamatsu, Wado, Koike, Masato
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986497/
https://ncbi.nlm.nih.gov/pubmed/33757554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00771-0
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