Establishment of an in vitro model for analyzing mitochondrial ultrastructure in PRKN-mutated patient iPSC-derived dopaminergic neurons

Mitochondrial structural changes are associated with the regulation of mitochondrial function, apoptosis, and neurodegenerative diseases. PRKN is known to be involved with various mechanisms of mitochondrial quality control including mitochondrial structural changes. Parkinson’s disease (PD) with PR...

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Dettagli Bibliografici
Pubblicato in:Mol Brain
Autori principali: Yokota, Mutsumi, Kakuta, Soichiro, Shiga, Takahiro, Ishikawa, Kei-ichi, Okano, Hideyuki, Hattori, Nobutaka, Akamatsu, Wado, Koike, Masato
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Methodology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986497/
https://ncbi.nlm.nih.gov/pubmed/33757554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00771-0
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