Establishment of an in vitro model for analyzing mitochondrial ultrastructure in PRKN-mutated patient iPSC-derived dopaminergic neurons

Mitochondrial structural changes are associated with the regulation of mitochondrial function, apoptosis, and neurodegenerative diseases. PRKN is known to be involved with various mechanisms of mitochondrial quality control including mitochondrial structural changes. Parkinson’s disease (PD) with PR...

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Vydáno v:Mol Brain
Hlavní autoři: Yokota, Mutsumi, Kakuta, Soichiro, Shiga, Takahiro, Ishikawa, Kei-ichi, Okano, Hideyuki, Hattori, Nobutaka, Akamatsu, Wado, Koike, Masato
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Methodology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986497/
https://ncbi.nlm.nih.gov/pubmed/33757554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00771-0
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