Purification of functional human ES and iPSC-derived midbrain dopaminergic progenitors using LRTM1

Human induced pluripotent stem cells (iPSCs) can provide a promising source of midbrain dopaminergic (mDA) neurons for cell replacement therapy for Parkinson's disease (PD). However, iPSC-derived donor cells inevitably contain tumorigenic or inappropriate cells. To eliminate these unwanted cell...

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Publicado no:Nat Commun
Main Authors: Samata, Bumpei, Doi, Daisuke, Nishimura, Kaneyasu, Kikuchi, Tetsuhiro, Watanabe, Akira, Sakamoto, Yoshimasa, Kakuta, Jungo, Ono, Yuichi, Takahashi, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067526/
https://ncbi.nlm.nih.gov/pubmed/27739432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13097
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