Selective and competitive inhibition of kynurenine aminotransferase 2 by glycyrrhizic acid and its analogues

The enzyme kynurenine aminotransferase (KAT) catalyses the conversion of kynurenine (KYN) to kynurenic acid (KYNA). Although the isozymes KAT1–4 have been identified, KYNA is mainly produced by KAT2 in brain tissues. KNYA is an antagonist of N-methyl-D-aspartate and α-7-nicotinic acetylcholine recep...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Yoshida, Yukihiro, Fujigaki, Hidetsugu, Kato, Koichi, Yamazaki, Kyoka, Fujigaki, Suwako, Kunisawa, Kazuo, Yamamoto, Yasuko, Mouri, Akihiro, Oda, Akifumi, Nabeshima, Toshitaka, Saito, Kuniaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629613/
https://ncbi.nlm.nih.gov/pubmed/31308447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46666-y
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi