A Lipid-encapsulated mRNA Encoding a Potently Neutralizing Human Monoclonal Antibody Protects Against Chikungunya Infection

Infection with chikungunya virus (CHIKV) typically causes an acute illness characterized by fever, rash, and arthralgia. However, CHIKV infection can sometimes progress to chronic arthritis or even lethal disease. CHIKV continues to cause significant morbidity worldwide as its vector mosquitoes expa...

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Vydáno v:Sci Immunol
Hlavní autoři: Kose, Nurgun, Fox, Julie M., Sapparapu, Gopal, Bombardi, Robin, Tennekoon, Rashika N., de Silva, A. Dharshan, Elbashir, Sayda M., Theisen, Matthew A., Humphris-Narayanan, Elisabeth, Ciaramella, Giuseppe, Himansu, Sunny, Diamond, Michael S., Crowe, James E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629435/
https://ncbi.nlm.nih.gov/pubmed/31101672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aaw6647
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