A Lipid-encapsulated mRNA Encoding a Potently Neutralizing Human Monoclonal Antibody Protects Against Chikungunya Infection

Infection with chikungunya virus (CHIKV) typically causes an acute illness characterized by fever, rash, and arthralgia. However, CHIKV infection can sometimes progress to chronic arthritis or even lethal disease. CHIKV continues to cause significant morbidity worldwide as its vector mosquitoes expa...

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Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Kose, Nurgun, Fox, Julie M., Sapparapu, Gopal, Bombardi, Robin, Tennekoon, Rashika N., de Silva, A. Dharshan, Elbashir, Sayda M., Theisen, Matthew A., Humphris-Narayanan, Elisabeth, Ciaramella, Giuseppe, Himansu, Sunny, Diamond, Michael S., Crowe, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629435/
https://ncbi.nlm.nih.gov/pubmed/31101672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aaw6647
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