A potently neutralizing human monoclonal antibody targeting an epitope in the West Nile virus E protein preferentially recognizes mature virions

West Nile virus (WNV), a member of the Flavivirus genus, is a leading cause of viral encephalitis in the United States(1). The development of neutralizing antibodies against the flavivirus envelope (E) protein is critical for immunity and vaccine protection(2). Previously identified candidate therap...

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Publicado no:Nat Microbiol
Main Authors: Goo, Leslie, Debbink, Kari, Kose, Nurgun, Sapparapu, Gopal, Doyle, Michael P., Wessel, Alex W., Richner, Justin M., Burgomaster, Katherine E., Larman, Bridget C., Dowd, Kimberly A., Diamond, Michael S., Crowe, James E., Pierson, Theodore C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435290/
https://ncbi.nlm.nih.gov/pubmed/30455471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-018-0283-7
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