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The Interferon-Stimulated Gene Ifi27l2a Restricts West Nile Virus Infection and Pathogenesis in a Cell-Type- and Region-Specific Manner

The mammalian host responds to viral infections by inducing expression of hundreds of interferon-stimulated genes (ISGs). While the functional significance of many ISGs has yet to be determined, their cell type and temporal nature of expression suggest unique activities against specific pathogens. U...

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Vydáno v:J Virol
Hlavní autoři: Lucas, Tiffany M., Richner, Justin M., Diamond, Michael S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810731/
https://ncbi.nlm.nih.gov/pubmed/26699642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02463-15
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