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The Interferon-Stimulated Gene Ifitm3 Restricts West Nile Virus Infection and Pathogenesis

The interferon-induced transmembrane protein (IFITM) family of proteins inhibit infection of several different enveloped viruses in cell culture by virtue of their ability to restrict entry and fusion from late endosomes. As few studies have evaluated the importance of Ifitm3 in vivo in restricting...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Gorman, Matthew J., Poddar, Subhajit, Farzan, Michael, Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008082/
https://ncbi.nlm.nih.gov/pubmed/27384652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00581-16
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