Dengue Virus prM-Specific Human Monoclonal Antibodies with Virus Replication-Enhancing Properties Recognize a Single Immunodominant Antigenic Site

The proposed antibody-dependent enhancement (ADE) mechanism for severe dengue virus (DENV) disease suggests that non-neutralizing serotype cross-reactive antibodies generated during a primary infection facilitate entry into Fc receptor bearing cells during secondary infection, resulting in enhanced...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Smith, Scott A., Nivarthi, Usha K., de Alwis, Ruklanthi, Kose, Nurgun, Sapparapu, Gopal, Bombardi, Robin, Kahle, Kristen M., Pfaff, Jennifer M., Lieberman, Sherri, Doranz, Benjamin J., de Silva, Aravinda M., Crowe, James E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2015
Aiheet:
Pathogenesis and Immunity
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702676/
https://ncbi.nlm.nih.gov/pubmed/26512092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01805-15
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