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Isolation of Dengue Virus-Specific Memory B Cells with Live Virus Antigen from Human Subjects following Natural Infection Reveals the Presence of Diverse Novel Functional Groups of Antibody Clones

Natural dengue virus (DENV) infection in humans induces antibodies (Abs) that neutralize the serotype of infection in a potent and type-specific manner; however, most Abs generated in response to infection are serotype cross-reactive and poorly neutralizing. Such cross-reactive Abs may enhance disea...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Smith, Scott A., de Alwis, A. Ruklanthi, Kose, Nurgun, Jadi, Ramesh S., de Silva, Aravinda M., Crowe, James E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248927/
https://ncbi.nlm.nih.gov/pubmed/25100837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00247-14
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