Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice

Zika virus (ZIKV) is an emerging mosquito-transmitted flavivirus that can cause severe disease, including congenital birth defects during pregnancy(1). To develop candidate therapeutic agents against ZIKV, we isolated a panel of human monoclonal antibodies from subjects that were previously infected...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Sapparapu, Gopal, Fernandez, Estefania, Kose, Nurgun, Cao, Bin, Fox, Julie M., Bombardi, Robin G., Zhao, Haiyan, Nelson, Christopher A., Bryan, Aubrey L., Barnes, Trevor, Davidson, Edgar, Mysorekar, Indira U., Fremont, Daved H., Doranz, Benjamin J., Diamond, Michael S., Crowe, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583716/
https://ncbi.nlm.nih.gov/pubmed/27819683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20564
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