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Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge
We previously generated a panel of human monoclonal antibodies (mAbs) against Zika virus (ZIKV) and identified one, ZIKV-116, that shares germline usage with mAbs identified in multiple donors. Here we show that ZIKV-116 interferes with ZIKV infection at a post-cellular attachment step by blocking v...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7041715/ https://ncbi.nlm.nih.gov/pubmed/31757867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191792 |
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