Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth

Broadly neutralizing antibodies (bNAbs) are rarely elicited by current human immunodeficiency virus type 1 (HIV-1) vaccine designs, but the presence of bNAbs in naturally infected individuals may be associated with high plasma viral loads, suggesting that the magnitude, duration, and diversity of vi...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Chukwuma, Valentine U., Kose, Nurgun, Sather, D. Noah, Sapparapu, Gopal, Falk, Rachel, King, Hannah, Singh, Vidisha, Lampley, Rebecca, Malherbe, Delphine C., Ditto, Noah T., Sullivan, Jonathan T., Barnes, Trevor, Doranz, Benjamin J., Labranche, Celia C., Montefiori, David C., Kalams, Spyros A., Haigwood, Nancy L., Crowe, James E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300260/
https://ncbi.nlm.nih.gov/pubmed/30566528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209437
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