Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth

Broadly neutralizing antibodies (bNAbs) are rarely elicited by current human immunodeficiency virus type 1 (HIV-1) vaccine designs, but the presence of bNAbs in naturally infected individuals may be associated with high plasma viral loads, suggesting that the magnitude, duration, and diversity of vi...

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Veröffentlicht in:PLoS One
Hauptverfasser: Chukwuma, Valentine U., Kose, Nurgun, Sather, D. Noah, Sapparapu, Gopal, Falk, Rachel, King, Hannah, Singh, Vidisha, Lampley, Rebecca, Malherbe, Delphine C., Ditto, Noah T., Sullivan, Jonathan T., Barnes, Trevor, Doranz, Benjamin J., Labranche, Celia C., Montefiori, David C., Kalams, Spyros A., Haigwood, Nancy L., Crowe, James E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300260/
https://ncbi.nlm.nih.gov/pubmed/30566528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209437
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