Envelope Variants Circulating as Initial Neutralization Breadth Developed in Two HIV-Infected Subjects Stimulate Multiclade Neutralizing Antibodies in Rabbits

Identifying characteristics of the human immunodeficiency virus type 1 (HIV-1) envelope that are effective in generating broad, protective antibodies remains a hurdle to HIV vaccine design. Emerging evidence of the development of broad and potent neutralizing antibodies in HIV-infected subjects sugg...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Malherbe, Delphine C., Pissani, Franco, Sather, D. Noah, Guo, Biwei, Pandey, Shilpi, Sutton, William F., Stuart, Andrew B., Robins, Harlan, Park, Byung, Krebs, Shelly J., Schuman, Jason T., Kalams, Spyros, Hessell, Ann J., Haigwood, Nancy L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249069/
https://ncbi.nlm.nih.gov/pubmed/25210191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01812-14
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