Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth

Several HIV envelope-targeting (Env-targeting) antibodies with broad and potent neutralizing activity have been identified and shown to have unusual features. Of these, the PG9 antibody has a long heavy chain complementarity determining region 3 (HCDR3) and possesses unique structural elements that...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Willis, Jordan R., Sapparapu, Gopal, Murrell, Sasha, Julien, Jean-Philippe, Singh, Vidisha, King, Hannah G., Xia, Yan, Pickens, Jennifer A., LaBranche, Celia C., Slaughter, James C., Montefiori, David C., Wilson, Ian A., Meiler, Jens, Crowe, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497764/
https://ncbi.nlm.nih.gov/pubmed/25985274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80693
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados