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Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth
Several HIV envelope-targeting (Env-targeting) antibodies with broad and potent neutralizing activity have been identified and shown to have unusual features. Of these, the PG9 antibody has a long heavy chain complementarity determining region 3 (HCDR3) and possesses unique structural elements that...
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| Yayımlandı: | J Clin Invest |
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| Asıl Yazarlar: | , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4497764/ https://ncbi.nlm.nih.gov/pubmed/25985274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80693 |
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