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Dose–response curve slope helps predict therapeutic potency and breadth of HIV broadly neutralizing antibodies
A new generation of HIV broadly neutralizing antibodies (bnAbs) with remarkable potency, breadth and epitope diversity has rejuvenated interest in immunotherapeutic strategies. Potencies defined by in vitro IC(50) and IC(80) values (50 and 80% inhibitory concentrations) figure prominently into the s...
Shranjeno v:
| izdano v: | Nat Commun |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Pub. Group
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4588098/ https://ncbi.nlm.nih.gov/pubmed/26416571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9443 |
| Oznake: |
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