Improving Neutralization Potency and Breadth by Combining Broadly Reactive HIV-1 Antibodies Targeting Major Neutralization Epitopes

The isolation of broadly neutralizing HIV-1 monoclonal antibodies (MAbs) to distinct epitopes on the viral envelope glycoprotein (Env) provides the potential to use combinations of MAbs for prevention and treatment of HIV-1 infection. Since many of these MAbs have been isolated in the last few years...

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書目詳細資料
發表在:J Virol
Main Authors: Kong, Rui, Louder, Mark K., Wagh, Kshitij, Bailer, Robert T., deCamp, Allan, Greene, Kelli, Gao, Hongmei, Taft, Justin D., Gazumyan, Anna, Liu, Cassie, Nussenzweig, Michel C., Korber, Bette, Montefiori, David C., Mascola, John R.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2014
主題:
Vaccines and Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325730/
https://ncbi.nlm.nih.gov/pubmed/25520506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03136-14
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