Improving Neutralization Potency and Breadth by Combining Broadly Reactive HIV-1 Antibodies Targeting Major Neutralization Epitopes

The isolation of broadly neutralizing HIV-1 monoclonal antibodies (MAbs) to distinct epitopes on the viral envelope glycoprotein (Env) provides the potential to use combinations of MAbs for prevention and treatment of HIV-1 infection. Since many of these MAbs have been isolated in the last few years...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Kong, Rui, Louder, Mark K., Wagh, Kshitij, Bailer, Robert T., deCamp, Allan, Greene, Kelli, Gao, Hongmei, Taft, Justin D., Gazumyan, Anna, Liu, Cassie, Nussenzweig, Michel C., Korber, Bette, Montefiori, David C., Mascola, John R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325730/
https://ncbi.nlm.nih.gov/pubmed/25520506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03136-14
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