Improving Neutralization Potency and Breadth by Combining Broadly Reactive HIV-1 Antibodies Targeting Major Neutralization Epitopes

The isolation of broadly neutralizing HIV-1 monoclonal antibodies (MAbs) to distinct epitopes on the viral envelope glycoprotein (Env) provides the potential to use combinations of MAbs for prevention and treatment of HIV-1 infection. Since many of these MAbs have been isolated in the last few years...

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Опубликовано в: :J Virol
Главные авторы: Kong, Rui, Louder, Mark K., Wagh, Kshitij, Bailer, Robert T., deCamp, Allan, Greene, Kelli, Gao, Hongmei, Taft, Justin D., Gazumyan, Anna, Liu, Cassie, Nussenzweig, Michel C., Korber, Bette, Montefiori, David C., Mascola, John R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
Предметы:
Vaccines and Antiviral Agents
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325730/
https://ncbi.nlm.nih.gov/pubmed/25520506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03136-14
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