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A single, continuous metric to define tiered serum neutralization potency against HIV

HIV-1 Envelope (Env) variants are grouped into tiers by their neutralization-sensitivity phenotype. This helped to recognize that tier 1 neutralization responses can be elicited readily, but do not protect against new infections. Tier 3 viruses are the least sensitive to neutralization. Because most...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Hraber, Peter, Korber, Bette, Wagh, Kshitij, Montefiori, David, Roederer, Mario
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788501/
https://ncbi.nlm.nih.gov/pubmed/29350181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31805
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