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Hitting the sweet spot: Exploiting HIV-1 glycan shield for induction of broadly neutralizing antibodies
PURPOSE OF REVIEW: The surface of the HIV-1 Env glycoprotein, the target of neutralizing antibodies, is extensively covered by N-linked glycans that create a glycan shield. Broadly neutralizing antibodies (bNAbs), the primary targets of HIV-1 vaccine design, have to negotiate this glycan shield. Her...
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| Veröffentlicht in: | Curr Opin HIV AIDS |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7877895/ https://ncbi.nlm.nih.gov/pubmed/32675574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/COH.0000000000000639 |
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