Загрузка...
Integrating linear optimization with structural modeling to increase HIV neutralization breadth
Computational protein design has been successful in modeling fixed backbone proteins in a single conformation. However, when modeling large ensembles of flexible proteins, current methods in protein design have been insufficient. Large barriers in the energy landscape are difficult to traverse while...
Сохранить в:
| Опубликовано в: : | PLoS Comput Biol |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2018
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5833279/ https://ncbi.nlm.nih.gov/pubmed/29451898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005999 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|