5′,8-Cyclopurine Lesions in DNA Damage: Chemical, Analytical, Biological, and Diagnostic Significance

Purine 5′,8-cyclo-2′-deoxynucleosides (cPu) are tandem-type lesions observed among the DNA purine modifications and identified in mammalian cellular DNA in vivo. These lesions can be present in two diasteroisomeric forms, 5′R and 5′S, for each 2′-deoxyadenosine and 2′-deoxyguanosine moiety. They are...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Chatgilialoglu, Chryssostomos, Ferreri, Carla, Geacintov, Nicholas E., Krokidis, Marios G., Liu, Yuan, Masi, Annalisa, Shafirovich, Vladimir, Terzidis, Michael A., Tsegay, Pawlos S.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628319/
https://ncbi.nlm.nih.gov/pubmed/31141888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8060513
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