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Increased levels of 5′,8-Cyclopurine DNA lesions in inflammatory bowel diseases
Chronic inflammation is estimated to be a causative factor in a variety of diseases. Under inflammatory conditions reactive oxygen species (ROS) and nitrogen species (RNS) are released leading to DNA damage accumulation and genomic instability. Purine 5′,8-cyclo-2′-deoxynucleosides (cPu) are oxidati...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2020-07-01
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| 叢編: | Redox Biology |
| 主題: | |
| 在線閱讀: | http://www.sciencedirect.com/science/article/pii/S2213231720303712 |
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