Oxygen-Dependent Accumulation of Purine DNA Lesions in Cockayne Syndrome Cells

Cockayne Syndrome (CS) is an autosomal recessive neurodegenerative premature aging disorder associated with defects in nucleotide excision repair (NER). Cells from CS patients, with mutations in CSA or CSB genes, present elevated levels of reactive oxygen species (ROS) and are defective in the repai...

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Bibliografske podrobnosti
izdano v:Cells
Main Authors: Krokidis, Marios G., D’Errico, Mariarosaria, Pascucci, Barbara, Parlanti, Eleonora, Masi, Annalisa, Ferreri, Carla, Chatgilialoglu, Chryssostomos
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407219/
https://ncbi.nlm.nih.gov/pubmed/32664519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9071671
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