Increased levels of 5′,8-Cyclopurine DNA lesions in inflammatory bowel diseases

Chronic inflammation is estimated to be a causative factor in a variety of diseases. Under inflammatory conditions reactive oxygen species (ROS) and nitrogen species (RNS) are released leading to DNA damage accumulation and genomic instability. Purine 5′,8-cyclo-2′-deoxynucleosides (cPu) are oxidati...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Masi, Annalisa, Fortini, Paola, Krokidis, Marios G., Romeo, Erminia Francesca, Bascietto, Cinzia, De Angelis, Paola, Guglielmi, Valeria, Chatgilialoglu, Chryssostomos
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225727/
https://ncbi.nlm.nih.gov/pubmed/32413746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101562
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