Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-β-Dependent Neuroectodermal Commitment

Gain of 20q11.21 is one of the most common recurrent genomic aberrations in human pluripotent stem cells. Although it is known that overexpression of the antiapoptotic gene Bcl-xL confers a survival advantage to the abnormal cells, their differentiation capacity has not been fully investigated. RNA...

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Xehetasun bibliografikoak
Argitaratua izan da:Stem Cell Reports
Egile Nagusiak: Markouli, C., De Deckersberg, E. Couvreu, Regin, M., Nguyen, H.T., Zambelli, F., Keller, A., Dziedzicka, D., De Kock, J., Tilleman, L., Van Nieuwerburgh, F., Franceschini, L., Sermon, K., Geens, M., Spits, C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627003/
https://ncbi.nlm.nih.gov/pubmed/31178415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.05.005
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