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The ESC: The Dangerous By-Product of V(D)J Recombination
V(D)J recombination generates antigen receptor diversity by mixing and matching individual variable (V), diversity (D), and joining (J) gene segments. An obligate by-product of many of these reactions is the excised signal circle (ESC), generated by excision of the DNA from between the gene segments...
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| Pubblicato in: | Front Immunol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6620893/ https://ncbi.nlm.nih.gov/pubmed/31333681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01572 |
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