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Transcription-coupled eviction of histones H2A/H2B governs V(D)J recombination

Initiation of V(D)J recombination critically relies on the formation of an accessible chromatin structure at recombination signal sequences (RSSs) but how this accessibility is generated is poorly understood. Immunoglobulin light-chain loci normally undergo recombination in pre-B cells. We show here...

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Main Authors: Bevington, Sarah, Boyes, Joan
格式: Artigo
語言:Inglês
出版: European Molecular Biology Organization 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655464/
https://ncbi.nlm.nih.gov/pubmed/23463099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.42
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