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Genome instability triggered by the V(D)J recombination by-product
A newly identified process by which mistargeted V(D)J recombination could cause genome instability in childhood leukemia has been discovered. In this mechanism, called cut-and-run, the excised DNA by-products of V(D)J recombination are re-bound by the recombinase proteins and erroneously trigger dou...
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| Pubblicato in: | Mol Cell Oncol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6548484/ https://ncbi.nlm.nih.gov/pubmed/31211241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1610323 |
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