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Genome instability triggered by the V(D)J recombination by-product

A newly identified process by which mistargeted V(D)J recombination could cause genome instability in childhood leukemia has been discovered. In this mechanism, called cut-and-run, the excised DNA by-products of V(D)J recombination are re-bound by the recombinase proteins and erroneously trigger dou...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Oncol
Egile Nagusiak: Kirkham, Christopher M., Boyes, Joan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548484/
https://ncbi.nlm.nih.gov/pubmed/31211241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1610323
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