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Regulation of V(D)J recombination by nucleosome positioning at recombination signal sequences

A key component in the regulation of V(D)J recombination is control of the accessibility of RAG proteins to recombination signal sequences (RSS). Nucleosomes are known to inhibit this accessibility. We show here that the signal sequence itself represses accessibility by causing nucleosome positionin...

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Detalhes bibliográficos
Main Authors: Baumann, Matthias, Mamais, Adamantios, McBlane, Fraser, Xiao, Hua, Boyes, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC204470/
https://ncbi.nlm.nih.gov/pubmed/14517257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg487
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