Regulation of V(D)J recombination by nucleosome positioning at recombination signal sequences

A key component in the regulation of V(D)J recombination is control of the accessibility of RAG proteins to recombination signal sequences (RSS). Nucleosomes are known to inhibit this accessibility. We show here that the signal sequence itself represses accessibility by causing nucleosome positionin...

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Detalles Bibliográficos

Publicado en:	EMBO J
Autores principales:	Baumann, Matthias, Mamais, Adamantios, McBlane, Fraser, Xiao, Hua, Boyes, Joan
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Publishing Group 2003
Materias:	Articles
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC204470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14517257/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg487
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