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Regulation of V(D)J recombination by nucleosome positioning at recombination signal sequences

A key component in the regulation of V(D)J recombination is control of the accessibility of RAG proteins to recombination signal sequences (RSS). Nucleosomes are known to inhibit this accessibility. We show here that the signal sequence itself represses accessibility by causing nucleosome positionin...

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Библиографические подробности
Главные авторы: Baumann, Matthias, Mamais, Adamantios, McBlane, Fraser, Xiao, Hua, Boyes, Joan
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2003
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC204470/
https://ncbi.nlm.nih.gov/pubmed/14517257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg487
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