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Genomic instability due to V(D)J recombination-associated transposition

The first step in assembling immunoglobulin and T-cell receptors by V(D)J recombination has similarities to transposon excision. The excised transposon-like element then integrates into DNA targets at random in vitro, but whether this activity significantly threatens the genomic integrity of its hos...

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Bibliografski detalji
Glavni autori: Reddy, Yeturu V.R., Perkins, Eric J., Ramsden
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482478/
https://ncbi.nlm.nih.gov/pubmed/16778076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1432706
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