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Genomic instability due to V(D)J recombination-associated transposition
The first step in assembling immunoglobulin and T-cell receptors by V(D)J recombination has similarities to transposon excision. The excised transposon-like element then integrates into DNA targets at random in vitro, but whether this activity significantly threatens the genomic integrity of its hos...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1482478/ https://ncbi.nlm.nih.gov/pubmed/16778076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1432706 |
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