Sensing of intermediates in V(D)J recombination by ATM

Ataxia-telangiectasia mutated (ATM) is required for resistance to radiation-induced DNA breaks. Here we use chromatin immunoprecipitation to show that ATM also localizes to breaks associated with V(D)J recombination. ATM recruitment to the recombining locus correlates approximately with recruitment...

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Bibliographic Details
Main Authors: Perkins, Eric J., Nair, Ayyappan, Cowley, Dale O., Van Dyke, Terry, Chang, Yung, Ramsden, Dale A.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2002
Subjects:
Research Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC155324/
https://ncbi.nlm.nih.gov/pubmed/11799059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.956902
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