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Cut-and-Run: A Distinct Mechanism by which V(D)J Recombination Causes Genome Instability
V(D)J recombination is essential to generate antigen receptor diversity but is also a potent cause of genome instability. Many chromosome alterations that result from aberrant V(D)J recombination involve breaks at single recombination signal sequences (RSSs). A long-standing question, however, is ho...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6509286/ https://ncbi.nlm.nih.gov/pubmed/30905508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.02.025 |
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