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Transcription-coupled eviction of histones H2A/H2B governs V(D)J recombination

Initiation of V(D)J recombination critically relies on the formation of an accessible chromatin structure at recombination signal sequences (RSSs) but how this accessibility is generated is poorly understood. Immunoglobulin light-chain loci normally undergo recombination in pre-B cells. We show here...

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Detalhes bibliográficos
Main Authors: Bevington, Sarah, Boyes, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655464/
https://ncbi.nlm.nih.gov/pubmed/23463099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.42
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