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The Impact of Pathogenic Mitochondrial DNA Mutations on Substantia Nigra Neurons

Mitochondrial defects within substantia nigra (SN) neurons are implicated in the pathogenesis of Parkinson's disease. SN neurons show increased mitochondrial defects, mitochondrial DNA deletion levels, and susceptibility to such dysfunction, although the role of mitochondria in neuronal degener...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Reeve, Amy, Meagher, Martin, Lax, Nichola, Simcox, Eve, Hepplewhite, Philippa, Jaros, Evelyn, Turnbull, Doug
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618501/
https://ncbi.nlm.nih.gov/pubmed/23804100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3525-12.2013
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