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The Impact of Pathogenic Mitochondrial DNA Mutations on Substantia Nigra Neurons

Mitochondrial defects within substantia nigra (SN) neurons are implicated in the pathogenesis of Parkinson's disease. SN neurons show increased mitochondrial defects, mitochondrial DNA deletion levels, and susceptibility to such dysfunction, although the role of mitochondria in neuronal degener...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Reeve, Amy, Meagher, Martin, Lax, Nichola, Simcox, Eve, Hepplewhite, Philippa, Jaros, Evelyn, Turnbull, Doug
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618501/
https://ncbi.nlm.nih.gov/pubmed/23804100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3525-12.2013
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