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The Impact of Pathogenic Mitochondrial DNA Mutations on Substantia Nigra Neurons

Mitochondrial defects within substantia nigra (SN) neurons are implicated in the pathogenesis of Parkinson's disease. SN neurons show increased mitochondrial defects, mitochondrial DNA deletion levels, and susceptibility to such dysfunction, although the role of mitochondria in neuronal degener...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Reeve, Amy, Meagher, Martin, Lax, Nichola, Simcox, Eve, Hepplewhite, Philippa, Jaros, Evelyn, Turnbull, Doug
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6618501/
https://ncbi.nlm.nih.gov/pubmed/23804100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3525-12.2013
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