Mitochondrial dysfunction within the synapses of substantia nigra neurons in Parkinson’s disease

Mitochondrial dysfunction within the cell bodies of substantia nigra neurons is prominent in both ageing and Parkinson’s disease. The loss of dopaminergic substantia nigra neurons in Parkinson’s disease is associated with loss of synapses within the striatum, and this may precede neuronal loss. We i...

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Publicado en:NPJ Parkinsons Dis
Autores principales: Reeve, Amy K., Grady, John P., Cosgrave, Eve M., Bennison, Emma, Chen, Chun, Hepplewhite, Philippa D., Morris, Christopher M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979968/
https://ncbi.nlm.nih.gov/pubmed/29872690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41531-018-0044-6
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